A college student complains of sore throat and nasal congestion. Which treatment is NOT appropriate for suspected viral URI?

In the context of treating a suspected viral upper respiratory infection (URI), oral prednisone, a corticosteroid, is not an appropriate treatment option. Corticosteroids like prednisone are typically used to reduce inflammation and suppress the immune response in conditions where an overactive immune response may cause harm, such as severe allergies, asthma exacerbations, or autoimmune diseases.

In cases of viral infections, the body’s immune response is essential for clearing the virus, and administering corticosteroids could hamper this response, leading to prolonged viral infection or increased risk of complications. Furthermore, systemic corticosteroids are not indicated for mild, self-limiting viral infections like the common cold.

On the other hand, saline nasal spray can help moisten nasal passages and alleviate congestion, pseudoephedrine is a decongestant that can provide temporary relief from nasal congestion, and ibuprofen can help relieve throat pain and fever due to its anti-inflammatory properties. All these treatments are supportive in managing the symptoms of a viral URI.